A survey and classification of software-defined storage systems

The exponential growth of digital information is imposing increasing scale and efficiency demands on modern storage infrastructures. As infrastructure complexity increases, so does the difficulty in ensuring quality of service, maintainability, and resource fairness, raising unprecedented performance, scalability, and programmability challenges. Software-Defined Storage (SDS) addresses these challenges by cleanly disentangling control and data flows, easing management, and improving control functionality of conventional storage systems. Despite its momentum in the research community, many aspects of the paradigm are still unclear, undefined, and unexplored, leading to misunderstandings that hamper the research and development of novel SDS technologies. In this article, we present an in-depth study of SDS systems, providing a thorough description and categorization of each plane of functionality. Further, we propose a taxonomy and classification of existing SDS solutions according to different criteria. Finally, we provide key insights about the paradigm and discuss potential future research directions for the field.This work was financed by the Portuguese funding agency FCT-Fundacao para a Ciencia e a Tecnologia through national funds, the PhD grant SFRH/BD/146059/2019, the project ThreatAdapt (FCT-FNR/0002/2018), the LASIGE Research Unit (UIDB/00408/2020), and cofunded by the FEDER, where applicable

Lustre: Building a File System for 1,000-node Clusters

Lustre is a GPLed cluster file system for Linux that is currently being tested on three of the world's largest Linux supercomputers, each with more than 1,000 nodes. In the past 18 months we've tried many tactics to scale to these limits, and the first half of this paper will discuss some of our successes and failures. The second half will explore some of the changes that we plan to make over the next year, as we scale towards tens of thousands of clients and petabytes of data

Self-Regulating Class E Resonant Power Converter Maintaining Operation in a Minimal Loss Region

A self-regulating Class E/resonant power converter includes a power switching device which is gated on at each transition between negative and positive half cycles of the load current by drive signals generated by a drive circuit, the rate at which the drive signals are generated being controlled by a zero crossing detector which monitors the load current and adjusts the frequency of the drive signals in correspondence with changes in the time between successive negative-to-positive zero crossings of the load current such that the power switching device continues to be switched on at substantially zero voltage, zero slope conditions to maintain the power converter operating at the optimal Class E frequency.Sponsorship: Illinois Institute of TechnologyUnited States Paten

Suspended Carrier Modulation of High-Q Transmitters

A method for on-off modulation of a transmitter coil current of a high-Q resonant circuit transmitter comprising the steps of sensing a zero-crossing of the transmitter coil current and substantially instantaneously interrupting the transmitter coil current, and a high-Q resonant circuit transmitter for carrying out said method.Sponsorship: Illinois Institute of TechnologySponsorship: United States of America as represented by the Department of Health and Human ServicesUnited States Paten

An endophytic fungus isolated from finger millet (Eleusine coracana) produces anti-fungal natural products Final Tech Annex 11

This research was supported by grants to MR by the Ontario Ministry of Agriculture and Food (OMAF), Grain Farmers of Ontario (GFO )and the Canadian International Development Research Centre (IDRC) and DFATD as part of the CIFSRFprogram.Finger millet is an ancient African cereal crop,domesticated 7000 years ago in Ethiopia,reaching India at 3000 BC. Finger millet is reported to be resistant to various fungal pathogens including Fusariumsp. We hypothesized that finger millet may host beneficial endophytes (plant-colonizing microbes) that contribute to the antifunga lactivity.Here we report the first isolation of endophyte(s) from finge rmillet. Five distinct fungal species were isolated from roots and predicted taxonomically based on 18Sr DNAsequencing

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Authors retain copyright to all submitted papers, but have granted unlimited redistribution rights to all as a condition of submission. Documentation/CodingStyle and Beyon

Glycerol-3-Phosphate Acquisition in Spirochetes: Distribution and Biological Activity of Glycerophosphodiester Phosphodiesterase (GlpQ) among Borrelia Species

Relapsing-fever spirochetes achieve high cell densities (>10(8)/ml) in their host's blood, while Lyme disease spirochetes do not (<10(5)/ml). This striking contrast in pathogenicity of these two groups of bacteria suggests a fundamental difference in their ability to either exploit or survive in blood. Borrelia hermsii, a tick-borne relapsing-fever spirochete, contains orthologs to glpQ and glpT, genes that encode glycerophosphodiester phosphodiesterase (GlpQ) and glycerol-3-phosphate transporter (GlpT), respectively. In other bacteria, GlpQ hydrolyzes deacylated phospholipids to glycerol-3-phosphate (G3P) while GlpT transports G3P into the cytoplasm. Enzyme assays on 17 isolates of borreliae demonstrated GlpQ activity in relapsing-fever spirochetes but not in Lyme disease spirochetes. Southern blots demonstrated glpQ and glpT in all relapsing-fever spirochetes but not in the Lyme disease group. A Lyme disease spirochete, Borrelia burgdorferi, that was transformed with a shuttle vector containing glpTQ from B. hermsii produced active enzyme, which demonstrated the association of glpQ with the hydrolysis of phospholipids. Sequence analysis of B. hermsii identified glpF, glpK, and glpA, which encode the glycerol facilitator, glycerol kinase, and glycerol-3-phosphate dehydrogenase, respectively, all of which are present in B. burgdorferi. All spirochetes examined had gpsA, which encodes the enzyme that reduces dihydroxyacetone phosphate (DHAP) to G3P. Consequently, three pathways for the acquisition of G3P exist among borreliae: (i) hydrolysis of deacylated phospholipids, (ii) reduction of DHAP, and (iii) uptake and phosphorylation of glycerol. The unique ability of relapsing-fever spirochetes to hydrolyze phospholipids may contribute to their higher cell densities in blood than those of Lyme disease spirochetes

Clonal Polymorphism of Borrelia burgdorferi Strain B31 MI: Implications for Mutagenesis in an Infectious Strain Background

A major obstacle to studying the functions of particular gene products in the mouse-tick infectious cycle of Borrelia burgdorferi has been an inability to knock out genes in pathogenic strains. Here, we investigated conditions for site-directed mutagenesis in B31 MI, the low-passage-number, infectious B. burgdorferi strain whose genome was sequenced. We inactivated several plasmid and chromosomal genes in B31 MI and determined that clones carrying these mutations were not infectious for mice. However, we found extensive heterogeneity among clones and mutants derived from B31 MI based on colony phenotype, growth rate, plasmid content, protein profile, and transformability. Significantly, several B31 MI clones that were not subjected to mutagenesis but that lacked particular plasmids also exhibited defects at various stages in the infectious cycle. Therefore, the high degree of clonal polymorphism within B31 MI complicates the assessment of the contributions of individual genes to the observed phenotypes of the mutants. Our results indicate that B31 MI is not an appropriate strain background for genetic studies in infectious B. burgdorferi, and a well-defined isogenic clone is a prerequisite for targeted mutagenesis. To this end, we derived several wild-type clones from B31 MI that were infectious for mice, and gene inactivation was successful in one of these clones. Due to the instability of the genome with in vitro propagation, careful monitoring of plasmid content of derived mutants and complementation of inactivated genes will be crucial components of genetic studies with this pathogen